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What is this blog about?
Well I’m late to the party. But that’s okay. This blog is a place for me to think out loud, to try out ideas, to share information and look for connections, especially among things that might not...
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Finding parallels between baseball and drug development
This piece was originally posted on Xconomy on March 1, 2013. The views in it are my own and do not necessarily reflect the views of Novo Nordisk. Consider a candidate. Selecting that candidate takes...
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Drug Development: Let’s Play!
This post appeared originally in Xconomy on March 21, 2013. The views expressed are my own and do not necessarily reflect those of Novo Nordisk. My son is addicted to “Let’s Play” videos on YouTube....
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Sequencing Seattle: An Idea for the Future of the Northwest
This post originally appeared on April 3, 2013 in Xconomy. The views presented are solely those of the author and do not necessarily reflect those of Novo Nordisk. What? Let me make a modest...
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Some thoughts in response to an article on why drug development is so hard
This comment was originally posted in response to an article by David Shaywitz at Forbes....
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Greenhouse Gas Is Changing Ocean Ecosystems
This article originally appeared in Real Change in 2005. I wrote it about one of my main concerns regarding climate change. The oceans have buffered the effects of man-made carbon dioxide in...
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I-5 as a metaphor for targets in drug development
All opinions are my own and not necessarily those of my employer. Yesterday a jack-knifed FedEx truck heading south on I-5 crashed as it passed Seattle’s downtown. Traffic backups spread for miles...
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Sea turtles: Nature’s smartphone
The recent publishing of the green sea turtle genome brought back memories of my first encounter with baby sea turtles, and one of the most fun and astonishing examples of hardwired behavior I know of....
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Supply chains in Drug Development?
This is a response I made to a recent post at Xconomy about the idea of drug development adopting a supply chain approach....
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The Global Alliance for responsible sharing of genomic and clinical data: an...
All opinions are my own and do not necessarily reflect those of Novo Nordisk I’ve been mulling over the recent announcement by several prominent genomics organizations of a set of standards for the...
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Reining in Hyperbole About the Role of Drug Development
All opinions expressed are my own and do not necessarily reflect those of Novo Nordisk “The traditional pharmaceutical research and development operating model is no longer sustainable,” says Dennis...
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A Genomics Researcher’s Take on the Global Health Metrics Conference 2013
All opinions are my own and do not necessarily reflect those of Novo Nordisk Over the past three days I had the opportunity to attend the Global Health Metrics Conference here in Seattle. This is not...
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Metrics and the Heisenberg quality of gathering data about behavior
All opinions are my own and do not necessarily reflect those of Novo Nordisk Thinking more about the Global Health Metrics Conference, one element that resonated was that measurement does not occur in...
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Gastric bypass surgery and the ever expanding world of GxE interactions
All opinions are my own and do not necessarily reflect those of Novo Nordisk. An early publication article from the Proceedings of the National Academy of Sciences reports the fascinating finding that...
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Why Derek Jeter being a lousy defensive shortstop gives me hope for...
All opinions are my own and do not necessarily reflect those of Novo Nordisk Hat tip to Jeff Sullivan of Fangraphs.com for the article that sparked this idea. It used to be we knew what a good defender...
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Cheetahs hunting and the quantified self
Who doesn’t love cheetahs? A young person of my acquaintance went so far as to spend a large portion of her time, at a certain age, cavorting on all fours and yipping and chirping like a cheetah. And...
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Cheetahs hunting redux: the next step in measuring baseball defense?
I had another thought about the collars that were used to measure cheetah hunting behaviors. For a summary that is not behind a paywall, see here. How long will it be before tools like these are used...
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Cheetahs hunting: a coda on sensors
I really need to keep up with my back issues of Wired. After posting about the possible use of portable sensors in sports to monitor defense and skills, I came across this feature in Wired about...
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Fielding percentage for UK surgeons
All opinions are my own and do not necessarily reflect those of Novo Nordisk. Last week I posted on how our measurements of defense in baseball have become a lot more sophisticated, and how that gave...
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3D printers, DIY Bio, French bistros and one possible future path for drug...
All opinions are my own and do not necessarily reflect those of Novo Nordisk The Long Tail is Everywhere There’s Information Several years ago I happened upon Chris Anderson’s great book The Long Tail....
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